Strategic Research Centre for Clinical Cancer Research
- Reference number
- A3 05:189
- Start and end dates
- 060101-121231
- Amount granted
- 55 000 000 SEK
- Administrative organization
- Lund University
- Research area
- Life Sciences
Summary
The translation of basic discoveries to the clinic is slow, expensive, and demanding as it requires multi-disciplinary collaborations involving basic researchers, clinicians, pathologists, patients, and regulatory bodies. CREATE (Clinical Research using Emerging Advanced Technologies for Health Biomarkers) is emerging as the most essential tool to boost efficiency in the field of prognostic diagnosis and of drug target discovery. Around 90 % of new chemical compounds fail during clinical trials and biomarkers have the potential to decrease this by identifying potential drug failures at an early stage, as well as providing clinicians with a predictive tool for patient stratification, using conventional drugs. The focus of CREATE Health is to address these problems by integrating cutting-edge technologies with clinical needs. The vision is to create a substantial social impact for the patient, through direct application of research for selection of an optimal, individually-based, cancer treatment and to develop novel diagnostics and therapeutics, based on identified markers and molecular signatures as well as potential targets, the latter through the participation of pharmaceutical industry. This will be achieved by bringing together both physically and logistically investigators from diverse fields, such as bioinformatics, nanotechnology, proteomics and transcriptomics with clinical oncology, cancer genetics and tumour cell biology.